医学书籍介绍

by Geoffrey M. Cooper, Robert E. Hausman

 "UNDERSTANDING THE MOLECULAR BIOLOGY OF CELLS is an active area of research that is fundamental to all of the biological sciences..."

“从分子生物学的角度理解细胞是所有生物科学的基础中有积极意义的研究”

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The cell

a molecular approach

  这是一本图文并茂的读物，从微观角度理解细胞的活动。十分有趣。

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细胞－－分子水平的结构

The cell -- a molecular approach

Preface

Organization and Features of The Cell

Acknowledgments

I. Introduction

1. An Overview of Cells and Cell Research

The Origin and Evolution of Cells

Cells As Experimental Models

Tools of Cell Biology

Summary

Questions

References and Further Reading

2. The Chemistry of Cells

The Molecular Composition of Cells

The Central Role of Enzymes as Biological Catalysts

Metabolic Energy

The Biosynthesis of Cell Constituents

Cell Membranes

Summary

Questions

References and Further Reading

3. Fundamentals of Molecular Biology

Heredity, Genes, and DNA

Expression of Genetic Information

Recombinant DNA

Detection of Nucleic Acids and Proteins

Gene Function in Eukaryotes

Summary

Questions

References and Further Reading

II. The Flow of Genetic Information

4. The Organization of Cellular Genomes

The Complexity of Eukaryotic Genomes

Chromosomes and Chromatin

The Sequences of Complete Genomes

The Human Genome

Summary

Questions

References and Further Reading

5. Replication, Maintenance, and Rearrangements of Genomic DNA

DNA Replication

DNA Repair

Recombination Between Homologous DNA Sequences

DNA Rearrangements

Summary

Questions

References and Further Reading

6. RNA Synthesis and Processing

Transcription in Prokaryotes

Eukaryotic RNA Polymerases and General Transcription Factors

Regulation of Transcription in Eukaryotes

RNA Processing and Turnover

Summary

Questions

References and Further Reading

      7. Protein Synthesis, Processing, and Regulation
         Translation of mRNA
         Protein Folding and Processing
         Regulation of Protein Function
         Protein Degradation
Summary
Questions
References and Further Reading

III. Cell Structure and Function

      8. The Nucleus
          The Nuclear Envelope and Traffic between the Nucleus and Cytoplasm
          Internal Organization of the Nucleus
          The Nucleolus
          The Nucleus during Mitosis
Summary
Questions
References and Further Reading

     9. Protein Sorting and Transport - The Endoplasmic Reticulum, Golgi Apparatus, and Lysosomes
         The Endoplasmic Reticulum
         The Golgi Apparatus
         The Mechanism of Vesicular Transport
         Lysosomes
Summary
Questions
References and Further Reading

     10. Bioenergetics and Metabolism - Mitochondria, Chloroplasts, and Peroxisomes
        Mitochondria
        The Mechanism of Oxidative Phosphorylation
        Chloroplasts and Other Plastids
        Photosynthesis
        Peroxisomes
Summary
Questions
References and Further Reading
　

    11. The Cytoskeleton and Cell Movement
          Structure and Organization of Actin Filaments
          Actin, Myosin, and Cell Movement
          Intermediate Filaments
          Microtubules
          Microtubule Motors and Movements
Summary
Questions
References and Further Reading

    12. The Cell Surface
          Structure of the Plasma Membrane
          Transport of Small Molecules
          Endocytosis
          Cell Walls and the Extracellular Matrix
          Cell-Cell Interactions
Summary
Questions
References and Further Reading
　

IV. Cell Regulation
      13. Cell Signaling
            Signaling Molecules and Their Receptors
            Functions of Cell Surface Receptors
            Pathways of Intracellular Signal Transduction
            Signal Transduction and the Cytoskeleton
            Signaling in Development and Differentiation
            Regulation of Programmed Cell Death
　

Summary
Questions
References and Further Reading

       14. The Cell Cycle
             The Eukaryotic Cell Cycle
             Regulators of Cell Cycle Progression
             The Events of M Phase
             Meiosis and Fertilization
             Cell Proliferation in Development and Differentiation
Summary
Questions
References and Further Reading

      15. Cancer
          The Development and Causes of Cancer
          Tumor Viruses
          Oncogenes
          Tumor Suppressor Genes
          Applications of Molecular Biology to Cancer Prevention and Treatment
Summary
Questions
References and Further Reading
Answers to Questions

Glossary         

　

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2007.3.6